The "Rune Best" is not just an enchantment. It is a statement. When Kratos speaks of "letting go of revenge," the player must now let go of their old, balanced builds. To defeat the impossible, you must become the impossible.
The “6666” in the patch number is not a coincidence. It points directly to a hexadecimal value in the game’s runic_effects.scl file. Players have since decoded this as the — a mechanic that allows certain Perk-based runes to stack at 66.6% efficacy up to four times (hence, 6666). god of war ragnarok update v1 0 622 6666rune best
The term “6666rune” does not refer to a single item. Instead, it is community slang for a new interaction layer introduced in v1.0.622.6666. Before this patch, most “on hit” or “on kill” runes had hard caps. You could not equip two runes of the same family for multiplicative benefits. The "Rune Best" is not just an enchantment
This is likely what you are searching for. The single best rune enchantment added in this patch is: To defeat the impossible, you must become the impossible
Best Runes After v1.0.622.6666 — God of War Ragnarök