If you are looking to use a 100% completion save or move data between devices:
By default, AetherSX2 stores everything in: /Internal Storage/AetherSX2/ resident evil 4 aethersx2 save data
immediately, you can download community-made saves from sites like If you are looking to use a 100%
If you have downloaded a save file from the internet (e.g., a "100% Complete" file to unlock the Chicago Typewriter or Infinite Launcher), it will usually come in one of two formats: .ps2 (Raw Memory Card) or .cbs /.max` (CodeBreaker/Action Replay formats). Do you need help finding a specific completed
Use the PCSX2 emulator and a tool called MyMC to open your .ps2 memory card file.
If the game freezes during a save/load operation, try switching the graphics backend to mode temporarily. Do you need help finding a specific completed save (like Professional mode cleared) or instructions on how to access the BIOS to format your memory card?